Frequency of microsatellite instability in gynecologic cancers and the efficacy of immune checkpoint inhibitors treated: real-world data from a single gynecologic center
This study had shown the MSI-H frequencies for the three major types of gynecological tumors and demonstrated the clinical benefit of treatment with ICIs in patients with advanced or recurrent gynecologic cancer. Among endometrial cancer patients, the effects of immunotherapy may be consistent regardless of MSI status.
Authors
- Dongni Liang
- Wei Kuang (ORCID: https://orcid.org/0000-0001-6615-8271)
- Jing Zeng (ORCID: https://orcid.org/0000-0001-8953-9042)
- Huanxin Sun
- Wei Wang (ORCID: https://orcid.org/0000-0002-0600-7276)
- Cheng Wang (ORCID: https://orcid.org/0009-0006-3379-1429)
- Qianqi Liu (ORCID: https://orcid.org/0000-0003-4950-9249)
- Lingling Tong (ORCID: https://orcid.org/0000-0003-4722-3167)
- Min Feng (ORCID: https://orcid.org/0009-0006-7527-0437)
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1567824
- Citations
- 2
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Sichuan University