A comprehensive evaluation of plasma metagenomics sequencing for the diagnosis of suspected infection in pediatric patients with hematologic diseases

Early plasma cfDNA mNGS improved the performance of pathogen detection in children with hematological diseases. Rapid identification of the pathogen followed by precise targeted antimicrobial therapy improves the prognosis of patients.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2025-05-09
DOI
https://doi.org/10.3389/fcimb.2025.1584214
Citations
2
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
2.71
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article

A comprehensive evaluation of plasma metagenomics sequencing for the diagnosis of suspected infection in pediatric patients with hematologic diseases

Wei Gai, Shihai Zhang, Qiang Guo, Yafeng Zheng et al.
2 citations
Frontiers in Cellular and Infection Microbiology
Cytomegalovirus and herpesvirus research
2.71
article

A comprehensive evaluation of plasma metagenomics sequencing for the diagnosis of suspected infection in pediatric patients with hematologic diseases

Wei Gai, Shihai Zhang, Qiang Guo, Yafeng Zheng, Yuxin Guo
article en
2 citations

Abstract

Early plasma cfDNA mNGS improved the performance of pathogen detection in children with hematological diseases. Rapid identification of the pathogen followed by precise targeted antimicrobial therapy improves the prognosis of patients.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Vision Technology (United States) (US)
Good health and well-being
Openalex Percentile: Top 11%
Cytomegalovirus and herpesvirus research
2.71
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