Study on the mechanism of <i>Xanthoceras sorbifolia</i> Bunge oil in the treatment of Alzheimer’s disease by an integrated “network pharmacology-metabolomics” strategy
This study demonstrated that XSBO has the potential to mitigate inflammation network disorders through the MAPK pathway and to restore sphingolipid metabolite levels in AD rats, thereby laying a groundwork for future studies.
Authors
- Yuanfang Sun
- Shikai Yan (ORCID: https://orcid.org/0000-0002-9816-4358)
- Leqi Wang
- Xue Xiao (ORCID: https://orcid.org/0000-0001-5890-844X)
- Xinyi Li (ORCID: https://orcid.org/0000-0002-0221-0525)
- Shasha Li (ORCID: https://orcid.org/0000-0003-1170-4591)
- Hui‐Zi Jin (ORCID: https://orcid.org/0000-0002-6901-5898)
- Yu Gan
- Lijing Du
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shanghai Jiao Tong University (CN)
- Guangdong Pharmaceutical University (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1080/07853890.2025.2499700
- Citations
- 1
- Primary Topic
- Lipid metabolism and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 1.11