Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients
Overall, this research primarily examines the intricate interplay between cell death processes and alterations in the immune microenvironment throughout the development of geriatric POD, pinpointing essential genes that provide vital theoretical support for further studies on geriatric POD. However, this discovery is only an initial one derived from analyzing the datasets. Upcoming research ought to evaluate and scrutinize additional datasets and conduct essential experiments to guarantee the precision and widespread relevance of the analytical findings.
Authors
- Xiaochuan Li (ORCID: https://orcid.org/0000-0002-6903-9574)
- Zhuoyue Gou
- Yao Wang (ORCID: https://orcid.org/0000-0003-4115-9571)
- Nan Su (ORCID: https://orcid.org/0000-0002-4564-1595)
- Shanshan Ren
- Lin Wang
- DanFeng Ren
Institutions
- Chongqing Emergency Medical Center (CN)
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fmed.2025.1580355
- Citations
- 2
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.09