Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients

Overall, this research primarily examines the intricate interplay between cell death processes and alterations in the immune microenvironment throughout the development of geriatric POD, pinpointing essential genes that provide vital theoretical support for further studies on geriatric POD. However, this discovery is only an initial one derived from analyzing the datasets. Upcoming research ought to evaluate and scrutinize additional datasets and conduct essential experiments to guarantee the precision and widespread relevance of the analytical findings.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-05-09
DOI
https://doi.org/10.3389/fmed.2025.1580355
Citations
2
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
3.09
Controls
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article

Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients

Xiaochuan Li, Zhuoyue Gou, Yao Wang, Nan Su et al.
2 citations
Frontiers in Medicine
Intensive Care Unit Cognitive Disorders
3.09
article

Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients

Xiaochuan Li, Zhuoyue Gou, Yao Wang, Nan Su, Shanshan Ren, Lin Wang, DanFeng Ren
article en
2 citations

Abstract

Overall, this research primarily examines the intricate interplay between cell death processes and alterations in the immune microenvironment throughout the development of geriatric POD, pinpointing essential genes that provide vital theoretical support for further studies on geriatric POD. However, this discovery is only an initial one derived from analyzing the datasets. Upcoming research ought to evaluate and scrutinize additional datasets and conduct essential experiments to guarantee the precision and widespread relevance of the analytical findings.

Frontiers in MedicineVol. 12
Chongqing Emergency Medical Center (CN), First People's Hospital of Chongqing (CN)
Good health and well-being
Openalex Percentile: Top 10%
Intensive Care Unit Cognitive Disorders
3.09
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Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients — Xiaochuan Li, Zhuoyue Gou, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS