Near-infrared fluorescent nanoprobe enables noninvasive, longitudinal monitoring of graft outcome in RPE transplantation
Near-infrared fluorescent nanoprobes represent a reliable method for <i>in vivo</i> tracing of donor RPE cells and long-term observation of nanoprobe distribution can be used to evaluate the degree of immune rejection. Molecular analysis of nanoprobe-labeled cells facilitates the characterization of the dynamic immune cell rejection niche and the landscape of donor-host interactions in RPE transplantation.
Authors
- Li‐Min Zheng (ORCID: https://orcid.org/0000-0003-4437-1105)
- Mengting Xue
- Songtao Yuan (ORCID: https://orcid.org/0000-0001-9212-0664)
- Rui Xie (ORCID: https://orcid.org/0000-0003-0357-6702)
- Lu Chen (ORCID: https://orcid.org/0000-0001-9222-8923)
- Weiqi Li (ORCID: https://orcid.org/0000-0002-7818-8627)
- Zhen Xu
- Min Wu (ORCID: https://orcid.org/0009-0002-9861-0204)
- Guandong Di
- Xiying Mao
- Xinpei Yuan
Institutions
- Inner Mongolia University of Science and Technology (CN)
- Baotou Medical College (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fmed.2025.1583790
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Nanjing Medical University