A Case Report of Chronic Kidney Disease Stage 5 Complicated with Uremic Tumor Calcinosis

Uremic tumor calcinosis (UTC) represents an extremely rare complication associated with chronic kidney disease (CKD), prominently characterized by the occurrence of ectopic calcification. The incidence of UTC among uremic peritoneal dialysis patients has been estimated to be approximately 1.60%. This specific case report aims to illuminate the intricate diagnostic and therapeutic challenges encountered in a dialysis patient. A 74-year-old male, diagnosed with stage 5 CKD and undergoing peritoneal dialysis, presented with a considerable 12x5 cm soft tissue mass on his back. Through a comprehensive array of imaging studies and histopathological examinations, the mass was subsequently identified as UTC. The diagnostic process revealed elevated levels of Parathyroid hormone (PTH) at 445.100 pg/ml and phosphorus at 2.77mg/dl. The diagnosis was ultimately confirmed via surgical resection. The patient's condition was managed and stabilized through the administration of phosphate binders and calcitriol. This case significantly underlines the critical necessity of vigilant and continuous monitoring of calcium-phosphorus metabolism in patients with CKD. Furthermore, it highlights UTC as an important differential diagnosis consideration when confronted with soft tissue masses.

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Publication Details

Journal
Modern Health Science
Published
2025-05-09
DOI
https://doi.org/10.30560/mhs.v8n2p43
Primary Topic
Parathyroid Disorders and Treatments
Type
article
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article

A Case Report of Chronic Kidney Disease Stage 5 Complicated with Uremic Tumor Calcinosis

Yu Wang, Wei Wei Li
Modern Health Science
Parathyroid Disorders and Treatments
article

A Case Report of Chronic Kidney Disease Stage 5 Complicated with Uremic Tumor Calcinosis

Yu Wang, Wei Wei Li
article en

Abstract

Uremic tumor calcinosis (UTC) represents an extremely rare complication associated with chronic kidney disease (CKD), prominently characterized by the occurrence of ectopic calcification. The incidence of UTC among uremic peritoneal dialysis patients has been estimated to be approximately 1.60%. This specific case report aims to illuminate the intricate diagnostic and therapeutic challenges encountered in a dialysis patient. A 74-year-old male, diagnosed with stage 5 CKD and undergoing peritoneal dialysis, presented with a considerable 12x5 cm soft tissue mass on his back. Through a comprehensive array of imaging studies and histopathological examinations, the mass was subsequently identified as UTC. The diagnostic process revealed elevated levels of Parathyroid hormone (PTH) at 445.100 pg/ml and phosphorus at 2.77mg/dl. The diagnosis was ultimately confirmed via surgical resection. The patient's condition was managed and stabilized through the administration of phosphate binders and calcitriol. This case significantly underlines the critical necessity of vigilant and continuous monitoring of calcium-phosphorus metabolism in patients with CKD. Furthermore, it highlights UTC as an important differential diagnosis consideration when confronted with soft tissue masses.

Modern Health ScienceVol. 8(2)
Binzhou People's Hospital (CN)
Openalex Percentile: Top 88%
Parathyroid Disorders and Treatments
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A Case Report of Chronic Kidney Disease Stage 5 Complicated with Uremic Tumor Calcinosis — Yu Wang, Wei Wei Li · Modern Health Science (2025) | TGRS Research Map | TGRS