Impact of pneumonitis from radiotherapy combined with immune checkpoint inhibitors therapy on tumor progression and survival in patients with non-small cell lung cancer
Pneumonitis resulting from TRT combined with ICIs was associated with shorter PFS but did not affect OS in NSCLC patients. Mixed pneumonitis did not worsen outcomes. Larger prospective studies are needed to validate these findings.
Authors
- Handong Sun (ORCID: https://orcid.org/0000-0002-2261-7103)
- Lühua Wang (ORCID: https://orcid.org/0000-0002-5272-1681)
- Ziwei Wang (ORCID: https://orcid.org/0000-0001-7813-4488)
- Jun Liang (ORCID: https://orcid.org/0000-0003-0309-0163)
- Kunpeng Xu (ORCID: https://orcid.org/0000-0001-9652-3284)
- Wei Jiang (ORCID: https://orcid.org/0000-0002-9027-4974)
Institutions
- Bengbu Medical College (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1578057
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Peking Union Medical College