Therapeutic effects and mechanisms of Fufang Longdan mixture on metabolic syndrome with psoriasis via miR-29a-5p/IGF-1R axis
Our findings demonstrate that FLM effectively ameliorates MS-P comorbidity through modulation of the miR-29a-5p/IGF-1R axis, showing significant therapeutic efficacy across different genetic backgrounds.
Authors
- Xuesong Yang (ORCID: https://orcid.org/0000-0002-2537-5752)
- Wen Huang
- Guangyun Luo (ORCID: https://orcid.org/0000-0002-8824-0601)
- Jianzhou Ye (ORCID: https://orcid.org/0000-0002-9205-4609)
- Xiangyi Kong (ORCID: https://orcid.org/0000-0002-8209-042X)
- Fang Wang (ORCID: https://orcid.org/0000-0002-9715-1838)
- Zhiming Wang (ORCID: https://orcid.org/0000-0001-7025-0185)
- Yiwen Zhang (ORCID: https://orcid.org/0000-0002-6928-8618)
- Zhuo Zhang (ORCID: https://orcid.org/0000-0001-6696-8282)
- Huan Cui (ORCID: https://orcid.org/0000-0002-1890-2243)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Yunnan University (CN)
- Kunming Medical University (CN)
- First People's Hospital of Yunnan Province (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fphar.2025.1585369
- Citations
- 2
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- Yunnan University
- Yunnan Provincial Science and Technology Department