Sanqi oral solution alleviates podocyte apoptosis in experimental membranous nephropathy by mediating EMT through the ERK/CK2-α/β-catenin pathway
Inhibition of EMT via the ERK/CK2-α/β-catenin pathway may be the main mechanism by which SQ suppresses podocyte apoptosis in IMN.
Authors
- Xiaowan Wang (ORCID: https://orcid.org/0000-0001-9152-8908)
- Peng Hui Xu (ORCID: https://orcid.org/0000-0002-9593-7167)
- Bidan Zheng
- Lihua Huang (ORCID: https://orcid.org/0000-0002-8943-8038)
- Bo Liu (ORCID: https://orcid.org/0000-0002-9539-2005)
- Ruimin Tian (ORCID: https://orcid.org/0000-0003-2740-5510)
- Wei Mao (ORCID: https://orcid.org/0000-0003-1994-2770)
- Yi Feng
- Juanjuan Wang (ORCID: https://orcid.org/0000-0002-0885-3521)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Guangdong Academy of Medical Sciences (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fphar.2025.1503961
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangdong Provincial Hospital of Traditional Chinese Medicine
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province