The effects of postponing BCG vaccination on the risk of BCG-related complications among patients with severe combined immunodeficiency disease in Saudi Arabia
Postponing BCG vaccination to 6 months of age significantly decreases the incidence of BCG-related complications in SCID patients and highlights the importance of tailoring vaccination schedules for high-risk populations. Early newborn screening and timely diagnosis of immunodeficiencies are essential to further minimize complications. The revised vaccination policy of Saudi Arabia provides a model for optimizing immunization strategies in regions with a high prevalence of inborn errors of immunity.
Authors
- Esam A. Albanyan
- Ohoud Alyabes (ORCID: https://orcid.org/0000-0003-1867-4815)
- Raghad Alonazi
- Nora Alrumayyan
- Sami Al-Hajjar (ORCID: https://orcid.org/0000-0003-4664-9748)
- Raghad Alhuthil (ORCID: https://orcid.org/0000-0001-6677-0452)
- Hamoud Al‐Mousa (ORCID: https://orcid.org/0000-0003-2508-0062)
- Sultan Albuhairi (ORCID: https://orcid.org/0000-0002-2779-8871)
- Mohammed Alsuhaibani (ORCID: https://orcid.org/0000-0003-3181-777X)
- Suliman Aljumaah (ORCID: https://orcid.org/0000-0002-5526-1174)
- Saeed Alamoudi (ORCID: https://orcid.org/0000-0001-8037-0738)
- Rand Arnaout (ORCID: https://orcid.org/0000-0003-3951-5880)
- Reem Mohammed (ORCID: https://orcid.org/0000-0002-5166-438X)
- Amal Aldhaheri
- Salem Saeed Alghamdi (ORCID: https://orcid.org/0000-0002-1654-3435)
- Bandar Al‐Saud
Institutions
- Alfaisal University (SA)
- King Abdulaziz University (SA)
- King Faisal Specialist Hospital & Research Centre (SA)
- King Abdulaziz Medical City (SA)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1596963
- Citations
- 4
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.19