The subsets of blood circulating T-cells associated with the development and prognosis of coinfection in patients with critical COVID-19
Our study found that lymphocyte subsets and cytokines play an important role in predicting bacterial coinfection in patients with critical COVID-19. Lower levels of CD4+ and CD8+ cells and higher level of IL4 and IL6 in patients on the day of admission were significantly correlated with the development of coinfection the following days in the hospital.
Authors
- Xingming Li
- Yunchuan Wang (ORCID: https://orcid.org/0000-0001-9183-9853)
- Jiayue Chen
- X. Yang (ORCID: https://orcid.org/0000-0002-7481-3149)
- Hong Peng (ORCID: https://orcid.org/0000-0003-0027-0855)
- Shiying He
Institutions
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1586302
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00