Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps
The results suggest that hBD-2 may partially attenuate the epithelial barrier disruption induced by MRSA, indicating the protective effect of hBD-2 on <i>S. aureus</i> infection.
Authors
- Xianyang Hu (ORCID: https://orcid.org/0000-0002-9163-509X)
- Ke‐Qing Zhao (ORCID: https://orcid.org/0000-0001-5703-3768)
- Yang Wu (ORCID: https://orcid.org/0000-0001-5356-2080)
- Sara Hsu (ORCID: https://orcid.org/0000-0002-9108-5411)
- Chunquan Zheng
- Qin Sun (ORCID: https://orcid.org/0000-0002-9699-6441)
- Tengfei Tian (ORCID: https://orcid.org/0000-0002-8029-3418)
- Yang Shi
Institutions
- Shanghai Medical College of Fudan University (CN)
- Eye & ENT Hospital of Fudan University (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fcimb.2025.1551080
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00