Salivary mycobiome alterations in HIV-infected MSM: dominance of Pseudogymnoascus and functional shifts across disease stages
Salivary mycobiome composition and function shift significantly across HIV stages, reflecting immune decline. <i>Pseudogymnoascus</i> dominance challenges conventional views of oral fungal ecology in immunocompromised hosts. These findings highlight the mycobiome's diagnostic potential for monitoring HIV-related oral health. Longitudinal studies are needed to validate clinical relevance.
Authors
- Lin Lü (ORCID: https://orcid.org/0000-0001-9573-1559)
- Xintong Sun
- Wenshan Duan (ORCID: https://orcid.org/0009-0000-5362-7024)
- Shan Guo (ORCID: https://orcid.org/0000-0001-6600-7131)
- Yixi Yu
- Zhen Fang (ORCID: https://orcid.org/0000-0002-6845-4354)
- Shuo Wen
- Wei Xia (ORCID: https://orcid.org/0000-0002-6070-9308)
- Yuchen Li (ORCID: https://orcid.org/0000-0001-7091-3073)
- Tao Huang (ORCID: https://orcid.org/0000-0002-2054-8087)
- Yan Wang (ORCID: https://orcid.org/0000-0002-8150-5486)
- Xin Wang (ORCID: https://orcid.org/0000-0003-4348-1767)
- Jie Cao (ORCID: https://orcid.org/0000-0002-0401-590X)
- Xiaojie Huang (ORCID: https://orcid.org/0000-0001-8267-9990)
- Ying Guo (ORCID: https://orcid.org/0000-0002-0368-5928)
- Junyi Duan
- Miao Zhang (ORCID: https://orcid.org/0000-0001-5490-1283)
- Feili Wei
- Dongxiang Zheng (ORCID: https://orcid.org/0000-0001-7384-3218)
- Meilin Guan
Institutions
- Capital Medical University (CN)
- Beijing YouAn Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fcimb.2025.1564891
- Primary Topic
- HIV/AIDS oral health manifestations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Municipal Health Commission
- Beijing Municipal Administration of Hospitals
- National Health Commission of the People's Republic of China