Kimura disease and eosinophilic granulomatosis with polyangiitis: Clinical and imaging overlap of 2 immune-mediated conditions

We present the clinical and head and neck imaging findings in an adult male patient diagnosed with both Kimura disease (KD) and eosinophilic granulomatosis with polyangiitis (EGPA). These 2 rare diseases have distinct as well as overlapping clinical features and pathophysiological mechanisms, and their coexistence created a challenging diagnostic and therapeutic scenario. This case highlights the importance of considering overlapping features in complex immune-mediated conditions to establish an accurate diagnosis and formulate an appropriate management plan.

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Publication Details

Journal
Radiology Case Reports
Published
2025-05-09
DOI
https://doi.org/10.1016/j.radcr.2025.04.060
Primary Topic
Vascular Tumors and Angiosarcomas
Type
article
Field-Weighted Citation Impact
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article

Kimura disease and eosinophilic granulomatosis with polyangiitis: Clinical and imaging overlap of 2 immune-mediated conditions

Sharon A. Chung, Beth A. Martin, Nancy J. Fischbein, Chris Holsinger et al.
Radiology Case Reports
Vascular Tumors and Angiosarcomas
article

Kimura disease and eosinophilic granulomatosis with polyangiitis: Clinical and imaging overlap of 2 immune-mediated conditions

Sharon A. Chung, Beth A. Martin, Nancy J. Fischbein, Chris Holsinger, Woon Kee Yoon, A LEE, Bader Abou Shaar
article en

Abstract

We present the clinical and head and neck imaging findings in an adult male patient diagnosed with both Kimura disease (KD) and eosinophilic granulomatosis with polyangiitis (EGPA). These 2 rare diseases have distinct as well as overlapping clinical features and pathophysiological mechanisms, and their coexistence created a challenging diagnostic and therapeutic scenario. This case highlights the importance of considering overlapping features in complex immune-mediated conditions to establish an accurate diagnosis and formulate an appropriate management plan.

Radiology Case ReportsVol. 20(7)
Cleveland Clinic (US), University of California, San Francisco (US), London North West Healthcare NHS Trust (GB), Stanford University (US)
Zero hunger
Openalex Percentile: Top 85%
Vascular Tumors and Angiosarcomas
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