Stage-dependent efficacy of short-chain fatty acids in amyotrophic lateral sclerosis: Insights into autophagy and neuroprotection
Our study revealed that the positive impact of SCFAs in autophagy could be a promising focus for ALS therapy. However, this effect might have different impacts in different stages of ALS.
Authors
- Jia Huo (ORCID: https://orcid.org/0000-0002-6187-3847)
- Cheng Xin
- Zikai Xin
- Rui Li (ORCID: https://orcid.org/0000-0001-7857-9735)
- Xin Li (ORCID: https://orcid.org/0000-0003-1631-7750)
- Yaling Liu (ORCID: https://orcid.org/0000-0002-6221-6021)
- Hui Dong (ORCID: https://orcid.org/0000-0001-6236-9805)
- Qi Liu (ORCID: https://orcid.org/0000-0003-4217-0641)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Life Sciences
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1016/j.lfs.2025.123686
- Citations
- 1
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39