NINJ1 impairs the anti-inflammatory function of hUC-MSCs with synergistic IFN-γ and TNF-α stimulation
Our findings shed new light on the immunomodulatory functions of cytokine-primed MSCs, offering groundbreaking insights for developing MSC-based therapies against inflammatory diseases via interfering the expression of NINJ1.
Authors
- Pei-Xin Shen (ORCID: https://orcid.org/0000-0002-5022-3654)
- Xiang Xu (ORCID: https://orcid.org/0000-0002-1026-2210)
- Luoquan Ao
- Yuchuan Yuan (ORCID: https://orcid.org/0000-0002-8289-7813)
- Mengwei Yao (ORCID: https://orcid.org/0000-0002-7484-8552)
- Jiaoyue Long
- Zhan Li (ORCID: https://orcid.org/0000-0001-5664-3863)
- Guomei Yang
- Hu Wang
Institutions
- Army Medical University (CN)
- Kunming Medical University (CN)
- Runze (China) (CN)
- Daping Hospital (CN)
Publication Details
- Journal
- Chinese Journal of Traumatology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1016/j.cjtee.2025.04.003
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63