Effectiveness of Allopurinol on Uric Acid and Pediatric Chronic Kidney Disease Severity in the Chronic Kidney Disease in Children Study
Allopurinol was effective at significantly lowering serum uric acid in children with CKD but was not associated with CKD progression measured by longitudinal eGFR and proteinuria.
Authors
- George J. Schwartz (ORCID: https://orcid.org/0000-0002-8291-1355)
- Matthew B. Matheson (ORCID: https://orcid.org/0009-0003-0354-1814)
- Bradley A. Warady (ORCID: https://orcid.org/0000-0003-1812-6587)
- Susan L. Furth (ORCID: https://orcid.org/0000-0003-2081-5242)
- Katherine E. Kurgansky (ORCID: https://orcid.org/0000-0001-9357-0034)
- Derek K. Ng (ORCID: https://orcid.org/0000-0001-5878-5101)
Institutions
- Children's Mercy Hospital (US)
- Children's Hospital of Philadelphia (US)
- Johns Hopkins University (US)
- University of Rochester Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1016/j.xkme.2025.101021
- Citations
- 1
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Children's Hospital of Philadelphia
- University of Missouri
- University of Minnesota
- Johns Hopkins University
- Children's Mercy Hospital
- Johns Hopkins Bloomberg School of Public Health
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute of Child Health and Human Development