Diagnostic Challenges in Philadelphia Chromosome-positive B-Lymphoblastic Leukemia/Lymphoma with Persistent <i>BCR::ABL1</i> Fusion after Treatment: A Pediatric Case Report
Philadelphia chromosome-positive (Ph+) B-lymphoblastic leukemia/lymphoma (B-ALL/LBL) is an aggressive hematologic malignancy driven by the BCR::ABL1 fusion. While many cases respond well to treatment, some patients exhibit persistent BCR::ABL1 expression after therapy, presenting significant diagnostic challenges.
Authors
- Wen Shuai (ORCID: https://orcid.org/0000-0001-7731-7186)
- Andrea Fuentes (ORCID: https://orcid.org/0000-0002-2112-071X)
- Wei Xie (ORCID: https://orcid.org/0000-0002-9179-4787)
- Qihan Guo (ORCID: https://orcid.org/0000-0002-4158-3623)
Publication Details
- Journal
- Journal of Clinical and Translational Pathology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.14218/jctp.2025.00012
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00