Changing trends in upper gastrointestinal endoscopic findings in Ethiopia: A comparison of eighteen thousand exams across two periods

This study sheds light on critical epidemiological shifts in upper GI diseases in Ethiopia, with a decline in peptic ulcer disease and a rise in portal hypertensive lesions and malignancies which have important public health implications. These findings underscore the need for increased awareness, improved clinical practices, enhanced resource allocation, and expanded access to early diagnosis and treatment of prevailing conditions. Preventive strategies targeting immunization and treatment of viral hepatitis, schistosomiasis, and <i>Helicobacter pylori</i> infection are urgently needed.