Perinatal Outcomes Related to the Presence of a Nuchal Cord During Delivery: A Retrospective Cohort Study

<b>Objective</b>: To evaluate and compare whether the presence of a nuchal cord (NC) and its characteristics had a negative impact on perinatal outcomes during delivery. <b>Methods</b>: This was a retrospective cohort study that analyzed the medical records of pregnant women from March 2020 to June 2023. Pregnant women were divided into groups with and without an NC. Singleton pregnancies ≥ 37 weeks were included, excluding fetal malformations, chromosomal anomalies, and cases with missing data and cord blood gas. <b>Results</b>: Of the 3364 medical records analyzed, 466 were included-366 without and 100 with an NC. Among the cases with an NC, 91% had one loop and 9% had ≥ two loops; 82% were loose and 18% were tight. Pregnant women with an NC had a higher gestational age (39.7 vs. 39.1 weeks, <i>p</i> = 0.006), fewer deliveries (1.0 vs. 2.0, <i>p</i> = 0.035), and a higher prevalence of cesarean sections (99% vs. 60.4%, <i>p</i> < 0.001). An NC was associated with a lower Apgar score at the 1st minute (8 vs. 9, <i>p</i> = 0.014) and higher arterial cord blood pH (7.27 vs. 7.24, <i>p</i> = 0.020). The presence of a tight cord was significantly associated with a 7.52-fold increased risk of an Apgar score < 7 at the 1st minute [x<sup>2</sup>(1) = 5.92, OR: 7.52, 95% CI: 1.51-37.31, R<sup>2</sup> Nagelkerke: 0.14, <i>p</i> = 0.014]. <b>Conclusions</b>: There was no effect of the presence of an NC on adverse perinatal outcomes. However, the presence of a tight NC was associated with an increased risk of an Apgar score < 7 at the 1st minute, but no other effect on neonatal outcomes.

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Publication Details

Journal
Diagnostics
Published
2025-05-09
DOI
https://doi.org/10.3390/diagnostics15101197
Citations
3
Primary Topic
Maternal and fetal healthcare
Type
article
Field-Weighted Citation Impact
10.48
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article

Perinatal Outcomes Related to the Presence of a Nuchal Cord During Delivery: A Retrospective Cohort Study

Gabriel Vinícius Rolim Silva, Gustavo Yano Callado, Edward Araujo Júnior, Alberto Borges Peixoto et al.
3 citations
Diagnostics
Maternal and fetal healthcare
10.48
article

Perinatal Outcomes Related to the Presence of a Nuchal Cord During Delivery: A Retrospective Cohort Study

Gabriel Vinícius Rolim Silva, Gustavo Yano Callado, Edward Araujo Júnior, Alberto Borges Peixoto, Mário Sérgio Gomes Caetano, Carolina Toledo Gontijo, Ana Paola Cruz Lunguinho
article en
3 citations

Abstract

<b>Objective</b>: To evaluate and compare whether the presence of a nuchal cord (NC) and its characteristics had a negative impact on perinatal outcomes during delivery. <b>Methods</b>: This was a retrospective cohort study that analyzed the medical records of pregnant women from March 2020 to June 2023. Pregnant women were divided into groups with and without an NC. Singleton pregnancies ≥ 37 weeks were included, excluding fetal malformations, chromosomal anomalies, and cases with missing data and cord blood gas. <b>Results</b>: Of the 3364 medical records analyzed, 466 were included-366 without and 100 with an NC. Among the cases with an NC, 91% had one loop and 9% had ≥ two loops; 82% were loose and 18% were tight. Pregnant women with an NC had a higher gestational age (39.7 vs. 39.1 weeks, <i>p</i> = 0.006), fewer deliveries (1.0 vs. 2.0, <i>p</i> = 0.035), and a higher prevalence of cesarean sections (99% vs. 60.4%, <i>p</i> < 0.001). An NC was associated with a lower Apgar score at the 1st minute (8 vs. 9, <i>p</i> = 0.014) and higher arterial cord blood pH (7.27 vs. 7.24, <i>p</i> = 0.020). The presence of a tight cord was significantly associated with a 7.52-fold increased risk of an Apgar score < 7 at the 1st minute [x<sup>2</sup>(1) = 5.92, OR: 7.52, 95% CI: 1.51-37.31, R<sup>2</sup> Nagelkerke: 0.14, <i>p</i> = 0.014]. <b>Conclusions</b>: There was no effect of the presence of an NC on adverse perinatal outcomes. However, the presence of a tight NC was associated with an increased risk of an Apgar score < 7 at the 1st minute, but no other effect on neonatal outcomes.

DiagnosticsVol. 15(10)
Universidade Municipal de São Caetano do Sul (BR), Hospital Israelita Albert Einstein (BR), Universidade Federal do Triângulo Mineiro (BR), Universidade de Uberaba (BR), Hospital São Paulo (BR), Universidade Federal de São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 2%
Maternal and fetal healthcare
10.48
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