Tumor-infiltrating CD4+ CD25+ FOXP3+ Treg is associated with plasma EBV DNA and disease progression in nasopharyngeal carcinoma
This study identified tumor-infiltrating CD4<sup>+</sup>CD25<sup>+</sup>FOXP3<sup>+</sup> Tregs as an independent negative prognostic factor for NPC progression and found higher Treg infiltration positively associated with plasma EBV DNA levels.
Authors
- Jie Yang (ORCID: https://orcid.org/0000-0002-5301-7610)
- Meng Yang (ORCID: https://orcid.org/0000-0003-0474-128X)
- Yoon Mee Yang (ORCID: https://orcid.org/0000-0003-4281-9906)
- Qianqian Qu
- Rui Hu (ORCID: https://orcid.org/0000-0002-5860-9148)
- Enzi Feng
- Xiaojiang Li (ORCID: https://orcid.org/0009-0009-7217-6957)
- Ling Tian
- Xinyu Yang (ORCID: https://orcid.org/0009-0002-6036-8942)
- Yanxin Ren
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Infectious Agents and Cancer
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1186/s13027-025-00660-4
- Citations
- 7
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 7.32
Funders
- National Natural Science Foundation of China