Three phloridzin derivatives capable of anti-oxidant from <i>Malus toringoides</i> (Rehd) Hughes
Two new phloridzin derivatives 6″-<i>O</i>-(4-hydroxytrans cinnamoyl) phloridzin (1) and 6″-<i>O</i>-(4-hydroxycis-cinnamoyl) phloridzin (3) and one known dihydrochalcones 6″-<i>O</i>-feruloyl phloroside (2) were isolated from the leaves of <i>Malus toringoides</i> (Rehd) Hughes. Their structures were elucidated on the basis of extensive spectroscopic data. The results of zebrafish and FRAP antioxidant kit showed that compound 1-3 had antioxidant effects.
Authors
- Junning Zhao (ORCID: https://orcid.org/0000-0002-8397-5350)
- Hua Hua (ORCID: https://orcid.org/0000-0003-2245-0101)
- Can Ren (ORCID: https://orcid.org/0009-0005-3264-0437)
- Jianbo Wang (ORCID: https://orcid.org/0000-0002-2666-2841)
- Liu L (ORCID: https://orcid.org/0000-0001-9234-457X)
- Dongmei Yu (ORCID: https://orcid.org/0000-0003-4380-1185)
- Yingchao Wang (ORCID: https://orcid.org/0000-0003-3590-9233)
- Weiwei Tian
Institutions
- Sichuan Academy of Traditional Chinese Medicine (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1080/14786419.2025.2494623
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China