Identifying suppressive factors of Alzheimer’s disease through comprehensive analysis of real-world data: a single-center retrospective study
This is the first human study to suggest that GA may be a factor that can suppress the onset of AD. Additionally, our method could be a promising tool for drug repositioning that applies existing drugs already used in clinical settings with well-known side effects to diseases different from their original use.
Authors
- Yoshiyasu Okuhara
- Masahide Shiotani (ORCID: https://orcid.org/0000-0001-9159-944X)
- Yuki Hyohdoh (ORCID: https://orcid.org/0000-0002-3108-2163)
- Hiroaki Kazui (ORCID: https://orcid.org/0000-0002-6838-8406)
- Yutaka Hatakeyama (ORCID: https://orcid.org/0000-0003-0004-5957)
Institutions
- Japanese Red Cross Kochi Hospital (JP)
- Kōchi University (JP)
Publication Details
- Journal
- BMC Geriatrics
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1186/s12877-025-05982-x
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Japan Society for the Promotion of Science