Analgesic Effect of the Chloroformic Extract of Aniba canelilla “canelon” Bark in BALB/c Mice

Background.Some diseases can cause intense pain, where pharmacological treatment with opioid analgesics is necessary, as in cancer.Despite advances in cancer treatment, pain is still a common symptom.Treatment is usually based on the use of opioids, but there is still some rejection because of their adverse effects or because of the delay in access to them.To evaluate the analgesic effect of Aniba canelilla "canelon" bark in mice to validate the above and consider it an alternative to existing palliative treatment in cancer patients.Methodology.The analgesic effect was evaluated according to the method of Koster et al. using 50 BALB/c mice distributed in groups of 07 mice each.Comparison was made with the standards Tramadol 50 mg/kg and Paracetamol 500 mg/kg administered orally, and acetic acid 0.8% was used intraperitoneally as a pain inducer.Results.The potent analgesic effect of the chloroformic extract of Aniba canelilla at 200mg/kg was observed, with an analgesic percentage of 98.87% with a mean number of writhes of 28.29 5.44, being statistically significant to the other treatments (p<0.01).Conclusions The analgesic effect of the chloroformic extract of Aniba canelilla at 200mg/kg was determined.

Authors

Publication Details

Journal
Pharmacognosy Journal
Published
2025-05-07
DOI
https://doi.org/10.5530/pj.2025.17.29
Primary Topic
Essential Oils and Antimicrobial Activity
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Analgesic Effect of the Chloroformic Extract of Aniba canelilla “canelon” Bark in BALB/c Mice

Jacobo Villalobos, Juana E. Chávez-Flores, Jesús Rojas‐Jaimes, Rosa Sánchez et al.
Pharmacognosy Journal
Essential Oils and Antimicrobial Activity
article

Analgesic Effect of the Chloroformic Extract of Aniba canelilla “canelon” Bark in BALB/c Mice

Jacobo Villalobos, Juana E. Chávez-Flores, Jesús Rojas‐Jaimes, Rosa Sánchez, A. Aliaga, Zulema Suricachi Cerron
article en

Abstract

Background.Some diseases can cause intense pain, where pharmacological treatment with opioid analgesics is necessary, as in cancer.Despite advances in cancer treatment, pain is still a common symptom.Treatment is usually based on the use of opioids, but there is still some rejection because of their adverse effects or because of the delay in access to them.To evaluate the analgesic effect of Aniba canelilla "canelon" bark in mice to validate the above and consider it an alternative to existing palliative treatment in cancer patients.Methodology.The analgesic effect was evaluated according to the method of Koster et al. using 50 BALB/c mice distributed in groups of 07 mice each.Comparison was made with the standards Tramadol 50 mg/kg and Paracetamol 500 mg/kg administered orally, and acetic acid 0.8% was used intraperitoneally as a pain inducer.Results.The potent analgesic effect of the chloroformic extract of Aniba canelilla at 200mg/kg was observed, with an analgesic percentage of 98.87% with a mean number of writhes of 28.29 5.44, being statistically significant to the other treatments (p<0.01).Conclusions The analgesic effect of the chloroformic extract of Aniba canelilla at 200mg/kg was determined.

Pharmacognosy JournalVol. 17(2)
Zero hunger
Openalex Percentile: Top 88%
Essential Oils and Antimicrobial Activity
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.