Chronic blue light exposure induced spatial anxiety in an adolescent mouse model: Per2 upregulation and altered brain resting-state functional activity
Our findings highlight that long-term BL exposure in adolescents induces spatial anxiety. The underlying mechanisms include changes in brain activity and connectivity and the disruption of the circadian rhythm.
Authors
- Hsin‐Su Yu (ORCID: https://orcid.org/0000-0002-9237-2260)
- Ying‐Shuang Chang
- Yu‐Lin Hsieh (ORCID: https://orcid.org/0000-0002-6380-3455)
- Li‐Wei Kuo (ORCID: https://orcid.org/0000-0002-0306-7329)
- Sheng-Min Huang
- Yu Kan (ORCID: https://orcid.org/0000-0002-9936-3375)
- Sebastian Yu (ORCID: https://orcid.org/0000-0002-2955-458X)
- Chia-Wen Chiang
- Tzu-Ning Chao
Institutions
- National Sun Yat-sen University (TW)
- Kaohsiung Medical University (TW)
- National Health Research Institutes (TW)
- National Cheng Kung University (TW)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121259
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 0.00