Walnut‐derived peptides combined with intermittent fasting alleviated obesity by modulating gut microbiota and liver metabolome in high‐fat‐diet‐induced obesity mice
The synergistic anti-obesity effects of WMP and IF are mediated through restoring gut microbial balance and reprogramming hepatic metabolic pathways. These findings highlight novel mechanisms involving the gut-liver axis, offering innovative strategies for obesity prevention through natural bioactive compounds combined with dietary interventions. © 2025 Society of Chemical Industry.
Authors
- Yuan Qi (ORCID: https://orcid.org/0009-0002-3599-284X)
- Jing Li (ORCID: https://orcid.org/0000-0001-9972-7397)
- Ji Wang
- Pan Hou
- Shihua Yin (ORCID: https://orcid.org/0000-0002-1184-1978)
- Lili Sun
- Zhenxu Deng
Institutions
- Jiangnan University (CN)
- Jilin Agricultural University (CN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1002/jsfa.14360
- Citations
- 2
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.33