Association between perfluoroalkyl and polyfluoroalkyl substances and adolescents' sleep disorders: NHANES 2005–2018

Our findings indicate a negative correlation between specific PFAS and specific sleep disorders in adolescents, with PFOS being the dominant effect component in the PFAS mixture and stronger effects observed in females. However, due to the cross-sectional nature of the study, a causal relationship cannot be established. These results highlight the potential public health impact of PFAS exposure and the need to further investigate the underlying mechanisms and causal pathways in future longitudinal or experimental studies.

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Publication Details

Journal
Frontiers in Nutrition
Published
2025-05-09
DOI
https://doi.org/10.3389/fnut.2025.1584281
Citations
2
Primary Topic
Per- and polyfluoroalkyl substances research
Type
article
Field-Weighted Citation Impact
1.72

Funders

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article

Association between perfluoroalkyl and polyfluoroalkyl substances and adolescents' sleep disorders: NHANES 2005–2018

Hong Yang, Yan Lu, Xiaoxiong Lai, Yanju Gong et al.
2 citations
Frontiers in Nutrition
Per- and polyfluoroalkyl substances research
1.72
article

Association between perfluoroalkyl and polyfluoroalkyl substances and adolescents' sleep disorders: NHANES 2005–2018

Hong Yang, Yan Lu, Xiaoxiong Lai, Yanju Gong, Bo Gao, Shen‐Ju Gou, Gan Luo
article en
2 citations

Abstract

Our findings indicate a negative correlation between specific PFAS and specific sleep disorders in adolescents, with PFOS being the dominant effect component in the PFAS mixture and stronger effects observed in females. However, due to the cross-sectional nature of the study, a causal relationship cannot be established. These results highlight the potential public health impact of PFAS exposure and the need to further investigate the underlying mechanisms and causal pathways in future longitudinal or experimental studies.

Frontiers in NutritionVol. 12
Chengdu University of Traditional Chinese Medicine (CN)
National Natural Science Foundation of China, Chengdu University of Traditional Chinese Medicine, Chengdu University, Natural Science Foundation of Sichuan Province
Good health and well-being
Openalex Percentile: Top 18%
Per- and polyfluoroalkyl substances research
1.72
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