Comment on “Main role of fractal-like nature of conformational space in subdiffusion in proteins”
Maggi and Orozco [Phys. Rev. E 109, 034402 (2024)10.1103/PhysRevE.109.034402] address the question of the origin of the subdiffusional dynamics observed in molecular dynamics (MD) simulations of proteins. Confirming the conclusions of previous publications that used closely similar methods [Neusius et al. Phys. Rev. Lett. 100, 188103 (2008)10.1103/PhysRevLett.100.188103; Phys. Rev. E 83, 021902 (2011)10.1103/PhysRevE.83.021902], Maggi and Orozco conclude that a random walk on a fractal surface is an appropriate model. However, the logic used in their paper to make that conclusion is erroneous.
Authors
- Jeremy C. Smith (ORCID: https://orcid.org/0000-0002-2978-3227)
- Igor M. Sokolov (ORCID: https://orcid.org/0000-0002-4688-9162)
- Thomas Neusius (ORCID: https://orcid.org/0000-0002-5097-9064)
Institutions
- Oak Ridge National Laboratory (US)
- Humboldt-Universität zu Berlin (DE)
- RheinMain University of Applied Sciences (DE)
- University of Tennessee at Knoxville (US)
Publication Details
- Journal
- Physical review. E
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1103/physreve.111.056401
- Primary Topic
- Protein Structure and Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00