Genome-wide expression in human whole blood for diagnosis of latent tuberculosis infection: a multicohort research
Our multicohort analysis established an NB-based diagnostic model utilizing S100A12/S100A8, which maintains diagnostic accuracy across diverse geographic, ethnic, and clinical variables (including HIV co-infection), highlighting its potential for clinical translation in LTBI/ATB differentiation.
Authors
- Ruizi Ni
- Fan Jiang (ORCID: https://orcid.org/0000-0002-9257-206X)
- Lingxia Zhang (ORCID: https://orcid.org/0000-0002-5012-7283)
- Linsheng Li (ORCID: https://orcid.org/0009-0009-8523-057X)
- Yajing An
- Yufeng Li (ORCID: https://orcid.org/0000-0002-7501-4621)
- Wenping Gong (ORCID: https://orcid.org/0000-0002-9334-0359)
- Yanhua Liu (ORCID: https://orcid.org/0000-0003-1104-284X)
Institutions
- Hebei North University (CN)
- Chinese People 's Liberation Army No. 85 Hospital (CN)
- China Electronics Standardization Institute (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fmicb.2025.1584360
- Citations
- 5
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 4.03