Matching plasma and tissue miRNA expression analysis to detect viable ovarian germ cell tumors
MiR-371-3 and miR-302/367 are highly expressed in ovarian VNTGC but not ITGC tumors, and their plasma levels correlate with disease burden. Future studies validating these findings in a larger cohort are needed to develop miRNAs as circulating biomarkers for clinical use.
Authors
- Sajjad Janfaza
- Arkhjamil Angeles (ORCID: https://orcid.org/0000-0003-1467-0075)
- Nastaran Khazamipour
- Mark Carey (ORCID: https://orcid.org/0000-0002-0473-6993)
- Craig R. Nichols (ORCID: https://orcid.org/0000-0002-6256-1511)
- Htoo Zarni Oo (ORCID: https://orcid.org/0009-0009-8514-2713)
- Güliz Özgün (ORCID: https://orcid.org/0000-0002-9575-8214)
- Lucia Nappi (ORCID: https://orcid.org/0000-0002-4365-7251)
- Christian Kollmannsberger (ORCID: https://orcid.org/0000-0002-6329-761X)
- Gurdial Dhillon
- Alireza Moeen
Institutions
- BC Cancer Agency (CA)
- University of British Columbia (CA)
- Testicular Cancer Commons (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1371/journal.pone.0322477
- Citations
- 1
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Health Research