Terpenes: natural compounds found in plants as potential senotherapeutics targeting senescent mesenchymal stromal cells and promoting apoptosis
These findings provide a detailed mechanistic dissection of terpene-induced senolysis and underscore their potential as promising candidates for senotherapeutics targeting senescent cells.
Authors
- Umberto Galderisi (ORCID: https://orcid.org/0000-0003-0909-7403)
- Chiara Schiraldi (ORCID: https://orcid.org/0000-0002-1066-843X)
- Valeria Mazzone (ORCID: https://orcid.org/0000-0002-4435-7023)
- Nicola Alessio (ORCID: https://orcid.org/0000-0002-5019-2130)
- Giovanni Galano
- Giovanni Di Bernardo (ORCID: https://orcid.org/0000-0002-4985-4029)
- Domenico Aprile (ORCID: https://orcid.org/0000-0003-1166-3259)
- Roberto De Rosa (ORCID: https://orcid.org/0000-0003-0318-1057)
Institutions
- Analysis and Monitoring of Environmental Risk (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Temple University (US)
- Erciyes University (TR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1186/s13287-025-04310-9
- Citations
- 6
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- European Commission
- Ministero dello Sviluppo Economico