Whole genome comparisons reveal gut-to-lung translocation of Escherichia coli and Burkholderia cenocepacia in two cases of ventilator-associated pneumonia in ICU patients
This study demonstrates the gut-to-lung translocation of E. coli and B. cenocepacia, highlighting their role in the development and progression of VAP in ICU patients. These findings provide valuable insights for implementing targeted prevention and treatment strategies for VAP in ICU settings.
Authors
- Yixin Liu (ORCID: https://orcid.org/0000-0002-1999-3175)
- Yi Luo (ORCID: https://orcid.org/0000-0001-7707-708X)
- Daqing Mao (ORCID: https://orcid.org/0000-0003-0313-0129)
- Lu Xing (ORCID: https://orcid.org/0000-0001-8621-6125)
- Xiaolong Wang (ORCID: https://orcid.org/0000-0002-3987-6638)
- Huihui Gao
- Huai Lin
- Lei Xu (ORCID: https://orcid.org/0000-0002-1742-4657)
- Yuting Gao (ORCID: https://orcid.org/0000-0002-1371-9917)
- Siyuan Zhu (ORCID: https://orcid.org/0000-0002-1743-1953)
Institutions
- Nankai University (CN)
- Tianjin Third Central Hospital (CN)
- Tianjin Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1186/s12931-025-03204-x
- Citations
- 1
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China