Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium

<b>Background:</b> Peripheral vein thrombosis during pregnancy poses serious diagnostic challenges due to the intertwining of its clinical symptoms with normal pregnancy modifications. <b>Methods:</b> We analyzed and compared the paraclinical test results of singleton pregnant women and women in the first six weeks postpartum who presented with significant lower limb inequality. <b>Results:</b> Our data revealed three predictors of deep vein thrombosis (DVT): mean platelet volume (MPV), with a one-unit increase in MPV being associated with a 1.497-fold higher risk of thrombosis (<i>p</i> = 0.008); platelet distribution width (PDW), with a one-unit decrease in PDW increasing thrombosis risk (odds ratio (OR) = 1.17, <i>p</i> = 0.003); anemia, with its presence increasing the risk of thrombosis by 8.46 times (<i>p</i> = 0.003); and fibrinogen, with a one-unit increase in its level increasing DVT risk 1.003-fold. <b>Conclusions:</b> Significant lower limb inequality might be used as a predictor of DVT during puerperium.

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Journal
Journal of Clinical Medicine
Published
2025-05-09
DOI
https://doi.org/10.3390/jcm14103320
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium

Cristina Furnică, Alexandra Ursache, Gabriele Anton, Cătălina Filip et al.
Journal of Clinical Medicine
Venous Thromboembolism Diagnosis and Management
article

Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium

Cristina Furnică, Alexandra Ursache, Gabriele Anton, Cătălina Filip, Raluca Ozana Chistol, Daniela Roxana Matasariu, Demetra Gabriela Socolov, Lucian Vasile Boiculese, Cristiana Filip
article en

Abstract

<b>Background:</b> Peripheral vein thrombosis during pregnancy poses serious diagnostic challenges due to the intertwining of its clinical symptoms with normal pregnancy modifications. <b>Methods:</b> We analyzed and compared the paraclinical test results of singleton pregnant women and women in the first six weeks postpartum who presented with significant lower limb inequality. <b>Results:</b> Our data revealed three predictors of deep vein thrombosis (DVT): mean platelet volume (MPV), with a one-unit increase in MPV being associated with a 1.497-fold higher risk of thrombosis (<i>p</i> = 0.008); platelet distribution width (PDW), with a one-unit decrease in PDW increasing thrombosis risk (odds ratio (OR) = 1.17, <i>p</i> = 0.003); anemia, with its presence increasing the risk of thrombosis by 8.46 times (<i>p</i> = 0.003); and fibrinogen, with a one-unit increase in its level increasing DVT risk 1.003-fold. <b>Conclusions:</b> Significant lower limb inequality might be used as a predictor of DVT during puerperium.

Journal of Clinical MedicineVol. 14(10)
Grigore T. Popa University of Medicine and Pharmacy (RO)
Good health and well-being
Openalex Percentile: Top 79%
Venous Thromboembolism Diagnosis and Management
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Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium — Cristina Furnică, Alexandra Ursache, et al. · Journal of Clinical Medicine (2025) | TGRS Research Map | TGRS