Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium
<b>Background:</b> Peripheral vein thrombosis during pregnancy poses serious diagnostic challenges due to the intertwining of its clinical symptoms with normal pregnancy modifications. <b>Methods:</b> We analyzed and compared the paraclinical test results of singleton pregnant women and women in the first six weeks postpartum who presented with significant lower limb inequality. <b>Results:</b> Our data revealed three predictors of deep vein thrombosis (DVT): mean platelet volume (MPV), with a one-unit increase in MPV being associated with a 1.497-fold higher risk of thrombosis (<i>p</i> = 0.008); platelet distribution width (PDW), with a one-unit decrease in PDW increasing thrombosis risk (odds ratio (OR) = 1.17, <i>p</i> = 0.003); anemia, with its presence increasing the risk of thrombosis by 8.46 times (<i>p</i> = 0.003); and fibrinogen, with a one-unit increase in its level increasing DVT risk 1.003-fold. <b>Conclusions:</b> Significant lower limb inequality might be used as a predictor of DVT during puerperium.
Authors
- Cristina Furnică (ORCID: https://orcid.org/0009-0004-4735-3425)
- Alexandra Ursache (ORCID: https://orcid.org/0000-0002-8207-7655)
- Gabriele Anton (ORCID: https://orcid.org/0000-0003-0483-892X)
- Cătălina Filip (ORCID: https://orcid.org/0000-0002-2132-6742)
- Raluca Ozana Chistol (ORCID: https://orcid.org/0000-0003-4225-1935)
- Daniela Roxana Matasariu (ORCID: https://orcid.org/0000-0002-2862-2069)
- Demetra Gabriela Socolov (ORCID: https://orcid.org/0000-0002-0979-0200)
- Lucian Vasile Boiculese (ORCID: https://orcid.org/0000-0001-5825-6189)
- Cristiana Filip
Institutions
- Grigore T. Popa University of Medicine and Pharmacy (RO)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3390/jcm14103320
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00