The genomic landscape of esophageal squamous cell carcinoma cell lines
The molecular profiles generated in this study provide detailed information on gene mutations and expression in common ESCC cell lines. The KYSE-150 cell line exhibited a prominent invasion capability, while the ECA-109 cell line showed up-regulated immune properties. This genomic landscape offers valuable insights for future research and therapeutic strategies in ESCC.
Authors
- Longlong Shao
- Kuaile Zhao (ORCID: https://orcid.org/0000-0001-8663-2874)
- Chenghao Li (ORCID: https://orcid.org/0000-0002-9060-9527)
- Jiaying Deng (ORCID: https://orcid.org/0000-0002-1744-1203)
- Jian Su (ORCID: https://orcid.org/0000-0002-1425-025X)
- Chao Zhang (ORCID: https://orcid.org/0009-0008-2674-344X)
Institutions
- Shanghai Medical College of Fudan University (CN)
- Harbin Institute of Technology (CN)
- Fudan University (CN)
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- Fudan University Shanghai Cancer Center (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1186/s12935-025-03686-1
- Citations
- 4
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- Fudan University