Feature Extraction through MS Lesion and Cerebral Lobe Segmentation for Enhanced EDSS Prediction

In this paper, we present a hybrid approach for segmenting multiple sclerosis (MS) lesions and predicting disability progression. Using Concat-UNet for accurate MS lesion segmentation and a multi-class UNet for brain lobe segmentation, we enable regional analysis of lesion impact. By fusing MRI, clinical, and demographic data, we enhanced EDSS prediction, with LightGBM achieving a high R2 score (0.96 ± 0.07)

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Published
2025-01-28
DOI
https://doi.org/10.1109/isnib64820.2025.10983385
Primary Topic
Brain Tumor Detection and Classification
Type
article
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article

Feature Extraction through MS Lesion and Cerebral Lobe Segmentation for Enhanced EDSS Prediction

Nada Haj Messaoud, Rihab Ben Dhia, Asma Ben Abdallah, Manel Mili et al.
Brain Tumor Detection and Classification
article

Feature Extraction through MS Lesion and Cerebral Lobe Segmentation for Enhanced EDSS Prediction

Nada Haj Messaoud, Rihab Ben Dhia, Asma Ben Abdallah, Manel Mili, Mohamed Hédi Bedoui, Neirez Zina
article en

Abstract

In this paper, we present a hybrid approach for segmenting multiple sclerosis (MS) lesions and predicting disability progression. Using Concat-UNet for accurate MS lesion segmentation and a multi-class UNet for brain lobe segmentation, we enable regional analysis of lesion impact. By fusing MRI, clinical, and demographic data, we enhanced EDSS prediction, with LightGBM achieving a high R2 score (0.96 ± 0.07)

University of Monastir (TN)
Openalex Percentile: Top 87%
Brain Tumor Detection and Classification
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