Prevalence of Peptic Ulcer Due to Helicobacter Pylori in Owerri, Imo State, Nigeria

Background: Peptic ulcer disease (PUD) caused by Helicobacter pylori (H. pylori) infection is a significant health issue globally. This study aims to determine the prevalence of H. pylori-associated peptic ulcers among individuals in Owerri West Local Government Area (LGA), Imo State, Nigeria. Materials and Methods: A descriptive cross-sectional design was employed, targeting individuals aged 18 years and above in Owerri West LGA. A sample size of 268 respondents was determined using the Yammane formula and selected through a multi-stage sampling method. Data collection involved a combination of serological tests for H. pylori and structured questionnaires covering socio-demographic details. Results: The study revealed a high prevalence of H. pylori infection among individuals diagnosed with peptic ulcer disease, with 82.5% testing positive for H. pylori. The demographic analysis showed a diverse population with the largest age group being 31-40 years old and a slight majority of female respondents. The high prevalence of H. pylori infection among individuals with peptic ulcers in Owerri West LGA highlights the need for effective diagnostic and management strategies. The study underscores the importance of accessible and reliable diagnostic methods, as well as comprehensive management approaches, to address the burden of H. pylori-associated peptic ulcers in the region.