Symptom Management for Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors: ASCO Guideline
Recommendations are included for carcinoid syndrome, carcinoid heart disease and carcinoid crisis, and functional pancreatic neuroendocrine tumor syndromes. Recommendations are provided for surgical management, liver-directed therapy, and systemic therapy options, as well as palliative care. Limited guidance is provided for sequencing of interventions.Additional information is available at www.asco.org/gastrointestinal-cancer-guidelines.
Authors
- Kimberly J. Perez (ORCID: https://orcid.org/0000-0002-5745-2994)
- Erik Mittra
- Julie Hallet (ORCID: https://orcid.org/0000-0001-5108-1072)
- Arvind N. Dasari (ORCID: https://orcid.org/0000-0001-5271-9744)
- Jana Ivanidze (ORCID: https://orcid.org/0000-0002-6470-5400)
- Jaydira Del Rivero (ORCID: https://orcid.org/0000-0001-9710-4030)
- Chandrika Chandrasekharan
- Sarah B. White (ORCID: https://orcid.org/0000-0002-6870-6400)
- Emily K. Bergsland (ORCID: https://orcid.org/0000-0001-7754-6552)
- Mark A. Lewis (ORCID: https://orcid.org/0000-0001-8633-6557)
- Namrata Vijayvergia (ORCID: https://orcid.org/0000-0001-6469-4759)
- Eva Tiensuu Janson (ORCID: https://orcid.org/0000-0002-1649-4880)
- Callisia N. Clarke (ORCID: https://orcid.org/0000-0002-5229-961X)
- Aman Chauhan (ORCID: https://orcid.org/0000-0002-4183-2116)
- James R. Howe (ORCID: https://orcid.org/0000-0001-5312-5972)
- Sandip Kanti Basu (ORCID: https://orcid.org/0000-0001-6607-2558)
- Heloisa P. Soares (ORCID: https://orcid.org/0000-0002-5185-2583)
- Nitya Raj (ORCID: https://orcid.org/0000-0002-1385-9995)
- Michael C. Soulen (ORCID: https://orcid.org/0000-0001-8136-2123)
- Junaid Arshad (ORCID: https://orcid.org/0000-0001-6576-3971)
- Jennifer A. Chan (ORCID: https://orcid.org/0000-0001-9798-1551)
- Jonathan Strosberg (ORCID: https://orcid.org/0000-0001-8405-218X)
- Erin E. Grady (ORCID: https://orcid.org/0000-0003-4857-2481)
- Josh Mailman (ORCID: https://orcid.org/0000-0002-7666-4386)
- Pamela L. Kunz (ORCID: https://orcid.org/0000-0002-9901-954X)
- Erin B. Kennedy (ORCID: https://orcid.org/0000-0002-4370-7757)
- Heidi M. Connolly (ORCID: https://orcid.org/0000-0003-0666-0344)
- Þorvarður R. Hálfdánarson (ORCID: https://orcid.org/0000-0001-8460-1257)
- Simron Singh (ORCID: https://orcid.org/0000-0002-5179-7043)
- Alexandra Gangi
Institutions
- Intermountain Healthcare (US)
- Uppsala University (SE)
- University of Iowa (US)
- Cedars-Sinai Medical Center (US)
- Fox Chase Cancer Center (US)
- American Society of Clinical Oncology (US)
- Sunnybrook Health Science Centre (CA)
- Bhabha Atomic Research Centre (IN)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Arizona (US)
- Oregon Health & Science University (US)
- University of California, San Francisco (US)
- Medical College of Wisconsin (US)
- Cornell University (US)
- University of Utah (US)
- Tata Memorial Hospital (IN)
- Huntsman Cancer Institute (US)
- Health Sciences Centre (CA)
- Moffitt Cancer Center (US)
- Yale University (US)
- University of Miami Health System (US)
- Dana-Farber Cancer Institute (US)
- Mayo Clinic in Arizona (US)
- Penn Center for AIDS Research (US)
- Stanford Medicine (US)
- National Cancer Institute (US)
- University of Pennsylvania Health System (US)
- Center for Cancer Research (US)
- Weill Cornell Medicine (US)
- University of Arizona Cancer Center
Publication Details
- Journal
- JCO Oncology Practice
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1200/op-25-00133
- Citations
- 6
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 8.13
Funders
- Bristol-Myers Squibb
- AstraZeneca
- Puma Biotechnology
- Seagen
- Astellas Pharma
- Oryzon Genomics
- Daiichi Sankyo Europe