Histomorphological changes in the wall of the pyeloureteral segment in young children

Purpose of the study. To study histo-morphological changes in the wall of the pyeloureteral segment in infants early age. Materials and Methods. The data of the results of comprehensive examination and surgical treatment of children aged from 1 month to 3 years who were treated in the urology department of the clinic of the Tashkent Pediatric Medical Institute (Tashkent Pediatric Medical Institute) and in the Training and Methodological Centre of Neonatal Surgery at the Republican Perinatal Centre (RPC) from 2014 to 2022 served as the material for the study. A retrospective and prospective analysis of clinical materials concerning the diagnosis and treatment of 131 children was performed. Among the patients, right-sided hydronephrosis was detected in 49 (37.4%) patients, left-sided obstruction in 73(55.7%) children, and 9 (6.9%) cases had bilateral lesions. Results. When analysing the characteristics of ureteral structural changes in age groups, it was found that in the group of children older than 1 year of age, the number of reversible and irreversible structural abnormalities did not differ significantly. In the age group of children under 1 year of age, the differences in the frequency of reversible and irreversible ureteral structural changes were statistically significant.