Palmitoylated COX-2Cys555 reprogrammed mitochondrial metabolism in pyroptotic inflammatory injury in patients with post-acute COVID-19 syndrome
This study highlights the regulatory role of COX-2<sup>Cys555</sup> palmitoylation in mitochondrial metabolism and lung inflammatory injury, and suggests potential therapeutic targets to combat respiratory pathogenesis linked to palmitoylated COX-2.
Authors
- Tianying Zhang (ORCID: https://orcid.org/0000-0002-2477-329X)
- Shengxiang Ge (ORCID: https://orcid.org/0000-0002-7165-3004)
- Kaili Yang (ORCID: https://orcid.org/0000-0003-0192-6326)
- Su-Min Mo
- Xin-Mou Wu
- Tingdong Li (ORCID: https://orcid.org/0000-0003-0685-2549)
- Jia‐Shen Wu
- Lin Che (ORCID: https://orcid.org/0009-0005-2619-9382)
- Chi-Yu Xu
- Zhong‐Ning Lin (ORCID: https://orcid.org/0000-0003-1717-0500)
- Ze‐Bang Du
- Yu-Chun Lin (ORCID: https://orcid.org/0009-0004-1686-5882)
- Yakun Zhang (ORCID: https://orcid.org/0000-0002-9636-8576)
Institutions
- Xiamen University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1016/j.jare.2025.05.005
- Citations
- 4
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.22