Effect of PUFAs-ω3 and ω6 on oxidative stress of sheep erythrocytes

Our results showed that a beneficial effect on the oxidative state of sheep RBCs was obtained with in vitro administration of low concentrations of ω6 and with all tested concentrations of ω3. The addition of ω6 at high concentrations leads to an imbalance in the PUFA ω3/ω6 ratio, compromising the oxidative state and viability of the RBCs. The maximum antioxidative effect was found at ω3/ω6 ratio 1:2).

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Publication Details

Journal
BMC Veterinary Research
Published
2025-05-10
DOI
https://doi.org/10.1186/s12917-025-04762-4
Primary Topic
Fatty Acid Research and Health
Type
article
Field-Weighted Citation Impact
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article

Effect of PUFAs-ω3 and ω6 on oxidative stress of sheep erythrocytes

Valeria Pasciu, Francesca Daniela Sotgiu, Fiammetta Berlinguer, Elena Baralla et al.
BMC Veterinary Research
Fatty Acid Research and Health
article

Effect of PUFAs-ω3 and ω6 on oxidative stress of sheep erythrocytes

Valeria Pasciu, Francesca Daniela Sotgiu, Fiammetta Berlinguer, Elena Baralla, Maria Nieddu, I. Contreras‐Solís
article en

Abstract

Our results showed that a beneficial effect on the oxidative state of sheep RBCs was obtained with in vitro administration of low concentrations of ω6 and with all tested concentrations of ω3. The addition of ω6 at high concentrations leads to an imbalance in the PUFA ω3/ω6 ratio, compromising the oxidative state and viability of the RBCs. The maximum antioxidative effect was found at ω3/ω6 ratio 1:2).

BMC Veterinary ResearchVol. 21(1)
University of Sassari (IT), Universidad Pública de Navarra (UPNA) (ES), Universidad de Navarra (ES)
Zero hunger
Openalex Percentile: Top 88%
Fatty Acid Research and Health
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Effect of PUFAs-ω3 and ω6 on oxidative stress of sheep erythrocytes — Valeria Pasciu, Francesca Daniela Sotgiu, et al. · BMC Veterinary Research (2025) | TGRS Research Map | TGRS