NAT10-mediated N4-acetylcytosine modification promotes the progression of retinoblastoma by improving the HK1 mRNA stability to enhance glycolysis

The authors illustrated that NAT10 plays an important role in the progression of RB by regulating the ac<sup>4</sup>C modification on HK1 mRNA and affects its stability, which may provide a novel theoretical basis for the treatment of RB.

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Publication Details

Journal
Clinics
Published
2025-01-01
DOI
https://doi.org/10.1016/j.clinsp.2025.100678
Citations
2
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
1.61
Controls
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article

NAT10-mediated N4-acetylcytosine modification promotes the progression of retinoblastoma by improving the HK1 mRNA stability to enhance glycolysis

Xuming Lin, Shan Xu, Fengyu Jia
2 citations
Clinics
RNA modifications and cancer
1.61
article

NAT10-mediated N4-acetylcytosine modification promotes the progression of retinoblastoma by improving the HK1 mRNA stability to enhance glycolysis

Xuming Lin, Shan Xu, Fengyu Jia
article en
2 citations

Abstract

The authors illustrated that NAT10 plays an important role in the progression of RB by regulating the ac<sup>4</sup>C modification on HK1 mRNA and affects its stability, which may provide a novel theoretical basis for the treatment of RB.

ClinicsVol. 80
Yuhuangding Hospital (CN)
Openalex Percentile: Top 17%
RNA modifications and cancer
1.61
DOIOpen Access PDFOpenAlex
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NAT10-mediated N4-acetylcytosine modification promotes the progression of retinoblastoma by improving the HK1 mRNA stability to enhance glycolysis — Xuming Lin, Shan Xu, et al. · Clinics (2025) | TGRS Research Map | TGRS