Antimicrobial susceptibility profile of Enterobacterales species isolated from blood cultures between 2016-2021

Aim: Blood culture is the gold standard in the diagnosis of bacteraemia and sepsis. When antimicrobial treatment is delayed, severe infections may occur, which may cause high morbidity and mortality. We aimed to determine the distribution of Enterobacterales isolates and their antimicrobial susceptibility profile from blood culture samples sent to the laboratory between 2016 and 2021. Material and Method: Enterobacterales isolated from blood culture samples sent to Ondokuz Mayis University Medical Microbiology laboratory between January 2016 and December 2021 was enrolled in the study. Vitek MS (BioMérieux, France) was used for identification of bacterial species and Vitek2 (BioMérieux, France) Compakt automated system were used for determination of antibiotic susceptibility of bacteria. EUCAST criteria were used for the evaluation of antibiotic susceptibility of the isolates. Results: The most three isolated bacteria were Escherichia coli, Klebsiella spp. and Enterobacter spp. respectively. The resistance rates were 9.06% for meropenem, 8.89% for imipenem and 15.67% for ertapenem, 7.57% and 6.28% for amikacin and tigecycline, respectively. Conclusion: Since the antibiotic resistance rates of the agents causing bloodstream infections show regional differences, it is thought that screening epidemiological data and reporting the results will increase the correct treatment rate and decrease the mortality rate.