CT-based quantification of intratumoral heterogeneity for predicting distant metastasis in retroperitoneal sarcoma
Preoperative identification of retroperitoneal sarcoma (RPS) with a high potential for distant metastasis (DM) is crucial for targeted interventional strategies. Quantitative assessment of intratumoral heterogeneity achieved reasonable performance for predicting DM. The integrated model combining clinicoradiological variables, ITH radiomics, and deep-learning features effectively predicted distant metastasis-free survival.
Authors
- Ning Lang (ORCID: https://orcid.org/0000-0003-1860-2918)
- S. Qin
- Haisong Chen (ORCID: https://orcid.org/0000-0002-4746-5193)
- Jianguo Miao (ORCID: https://orcid.org/0000-0002-1607-8633)
- Yupeng Zhu
- Ke Liu (ORCID: https://orcid.org/0000-0001-5407-3860)
- Chenxi Wang (ORCID: https://orcid.org/0000-0002-9547-1547)
- Jun Xu (ORCID: https://orcid.org/0000-0002-1823-3633)
Institutions
- Qingdao University (CN)
- Qingdao University of Science and Technology (CN)
- Peking University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Peking University Third Hospital (CN)
- Shandong University of Science and Technology (CN)
Publication Details
- Journal
- Insights into Imaging
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1186/s13244-025-01977-9
- Citations
- 2
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China