Potential Key Genes for Giant Cell Arteritis Revealed Based on Single-Cell Sequencing and Mendelian Randomization Analysis
This study identified three potential key genes (RCAN3, RPS6, and HLA-DQB1) linked to the causality of GCA, providing new perspectives on the pathogenesis of GCA and new avenues for therapeutic strategies.
Authors
- Shushan Sang (ORCID: https://orcid.org/0000-0002-2297-9737)
- Bochao Jia (ORCID: https://orcid.org/0009-0006-8997-7839)
- Joseph Chen (ORCID: https://orcid.org/0009-0002-3715-3871)
- Yunkai Wang (ORCID: https://orcid.org/0000-0002-2979-1569)
- Yuanhui Hu (ORCID: https://orcid.org/0000-0001-6118-8009)
- Tao Cheng (ORCID: https://orcid.org/0000-0002-3056-8137)
- X. H. Shan
- Wei Yi
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1159/000546323
- Citations
- 1
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.52