Epstein–Barr virus reactivation after haplo-peripheral blood stem cell transplantation in patients with hematological malignancies: immune reconstitution and influence on survival
Our study showed EBV IgA-negative donor, CMV reactivation, and GVHD prophylaxis with ATG were independent risk factors of EBV reactivation. Posttransplant EBV reactivation had no significant influence on the outcomes of patients, but its impact on immune reconstitution might be complicated. The predictive model based on the study could direct our attention toward patients at high risk of EBV reactivation.
Authors
- Junyou Yang (ORCID: https://orcid.org/0000-0003-0849-1492)
- Jie Shao (ORCID: https://orcid.org/0009-0002-1896-9496)
- Liping Wan (ORCID: https://orcid.org/0000-0001-6868-0258)
- Min Yang (ORCID: https://orcid.org/0000-0001-9491-3385)
- Xianmin Song (ORCID: https://orcid.org/0000-0003-0637-5324)
- Yu Cai (ORCID: https://orcid.org/0000-0001-8804-2616)
- Chongmei Huang (ORCID: https://orcid.org/0000-0001-6794-0724)
- Ying Zhang (ORCID: https://orcid.org/0000-0003-1936-6101)
- Ting Wang (ORCID: https://orcid.org/0000-0002-7787-1192)
- Ling Ma (ORCID: https://orcid.org/0000-0002-9649-0002)
- Kun Zhou (ORCID: https://orcid.org/0000-0001-7660-2911)
- Jingjing Cao (ORCID: https://orcid.org/0000-0003-4931-8717)
- Yin Tong (ORCID: https://orcid.org/0000-0001-7551-5509)
- Huiying Qiu (ORCID: https://orcid.org/0000-0001-5211-725X)
- Xiaowei Xu (ORCID: https://orcid.org/0000-0003-4098-7690)
- Yu Wei
- Jiahua Niu
- Xinxin Xia
- Chang Shen
Institutions
- Sun Yat-sen University (CN)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- Therapeutic Advances in Hematology
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1177/20406207251335477
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00