Individualized MRI-Based Stroke Prediction Score Using Plaque Vulnerability for Symptomatic Carotid Artery Disease Patients (IMPROVE)
Using the presence of intraplaque hemorrhage on magnetic resonance imaging and 4 conventional parameters, the IMPROVE model provides accurate individual stroke risk estimates, which may facilitate stratification for revascularization after external validation.
Authors
- Pim A. de Jong (ORCID: https://orcid.org/0000-0003-4840-6854)
- M. Eline Kooi (ORCID: https://orcid.org/0000-0001-7562-5724)
- Luc Smits (ORCID: https://orcid.org/0000-0003-0785-1345)
- Akram A. Hosseini (ORCID: https://orcid.org/0000-0003-0133-9842)
- Robert M. Kwee (ORCID: https://orcid.org/0000-0001-7760-867X)
- Dianne H.K. van Dam-Nolen (ORCID: https://orcid.org/0000-0002-4527-3876)
- Kelly Nies (ORCID: https://orcid.org/0000-0002-9457-3306)
- Dorothee P. Auer (ORCID: https://orcid.org/0000-0002-4745-3635)
- Yoshitaka Kurosaki (ORCID: https://orcid.org/0000-0003-0738-760X)
- Sander M. J. van Kuijk (ORCID: https://orcid.org/0000-0003-2796-729X)
- Robert J. van Oostenbrugge (ORCID: https://orcid.org/0000-0003-1032-9099)
- Daniël Bos (ORCID: https://orcid.org/0000-0001-8979-2603)
- Andreas Schindler (ORCID: https://orcid.org/0000-0003-0183-5782)
- Iris Rupert
- Paul J. Nederkoorn
- Sen Yamagata
- Tobias Saam
Institutions
- Nottingham University Hospitals NHS Trust (GB)
- University of Nottingham (GB)
- Maastricht University Medical Centre (NL)
- Erasmus MC (NL)
- University Medical Center Utrecht (NL)
- LMU Klinikum (DE)
- Maastricht University (NL)
- Kurashiki Central Hospital (JP)
- Ihre-Radiologen (DE)
- Department of Health (TW)
- Zuyderland Medisch Centrum (NL)
- Nottingham Biomedical Research Centre (GB)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Stroke
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1161/strokeaha.124.050020
- Citations
- 11
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 16.70
Funders
- Eli Lilly and Company
- Biogen
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Eisai
- National Institutes of Health
- Medical Research Council