[68Ga]-DOTATOC PET/CT and Clear Cell Renal Cell Carcinoma Metastasis: Simple False Positive or Potential Staging Imaging?

Clear cell renal cell carcinoma is the most common type of kidney cancer. Apart of lymph nodes, the frequent metastatic sites are lung, bone and, more rarely, pancreas. These three sites of involvement are also common for NETs. This well-differentiated tumour has a low FDG avidity. We report two clinical cases of pancreatic and pulmonary lesions, suspicious of NET but with a history of clear cell renal cell carcinoma. [68Ga]-DOTATOC PET/CT find strong uptakes but biopsies ultimately revealed metastases of clear cell renal cell carcinoma.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-05-09
DOI
https://doi.org/10.1097/rlu.0000000000005949
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

[68Ga]-DOTATOC PET/CT and Clear Cell Renal Cell Carcinoma Metastasis: Simple False Positive or Potential Staging Imaging?

Anthime Flaus, Sibel Isal, Isabelle Morelec, Nicolas Jacquet-Francillon et al.
Clinical Nuclear Medicine
Renal cell carcinoma treatment
article

[68Ga]-DOTATOC PET/CT and Clear Cell Renal Cell Carcinoma Metastasis: Simple False Positive or Potential Staging Imaging?

Anthime Flaus, Sibel Isal, Isabelle Morelec, Nicolas Jacquet-Francillon, Chawki Ghayor, Mathilde Vergoby
article en

Abstract

Clear cell renal cell carcinoma is the most common type of kidney cancer. Apart of lymph nodes, the frequent metastatic sites are lung, bone and, more rarely, pancreas. These three sites of involvement are also common for NETs. This well-differentiated tumour has a low FDG avidity. We report two clinical cases of pancreatic and pulmonary lesions, suspicious of NET but with a history of clear cell renal cell carcinoma. [68Ga]-DOTATOC PET/CT find strong uptakes but biopsies ultimately revealed metastases of clear cell renal cell carcinoma.

Clinical Nuclear MedicineVol. 50(11)
Université Claude Bernard Lyon 1 (FR), Hospices Civils de Lyon (FR), Hôpital Lyon Sud (FR)
Good health and well-being
Openalex Percentile: Top 85%
Renal cell carcinoma treatment
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