The MYC/TXNIP axis mediates NCL-Suppressed CD8+T cell immune response in lung adenocarcinoma
NCL overexpression suppresses CD8<sup>+</sup> T cell glucose metabolism and anti-tumor immune function, promoting lung adenocarcinoma progression via the MYC/TXNIP axis.
Authors
- Dan Xiao (ORCID: https://orcid.org/0009-0008-0042-3763)
- Yigang Liu (ORCID: https://orcid.org/0000-0003-2067-7249)
- Tanxiu Chen (ORCID: https://orcid.org/0000-0003-4877-9423)
- Wei Yan (ORCID: https://orcid.org/0000-0003-3978-7675)
- Xinlin Yu (ORCID: https://orcid.org/0000-0002-3622-8416)
- Ying Song (ORCID: https://orcid.org/0000-0002-4533-3525)
Institutions
- Jiangxi Provincial Academy of Medical Sciences (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1186/s10020-025-01224-3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Jiangxi Province