Maintenance of Remission After Tocilizumab Withdrawal in Patients With Glucocorticoid‐Dependent Polymyalgia Rheumatica
Among patients with GC-dependent PMR in remission after a six-month TCZ treatment, only a minority of the patients remained relapse-free after TCZ discontinuation. This study suggests that a six-month treatment course is not long enough to withdraw the TCZ. Further studies are needed to determine the optimal TCZ treatment duration and strategies for cessation to prevent relapses.
Authors
- Divi Cornec (ORCID: https://orcid.org/0000-0002-9159-702X)
- Aghiles Souki
- Catherine Le Hénaff
- Thierry Marhadour (ORCID: https://orcid.org/0000-0003-1676-987X)
- Bruno Fautrel (ORCID: https://orcid.org/0000-0001-8845-4274)
- Baptiste Chevet (ORCID: https://orcid.org/0000-0002-9646-7603)
- Daniel Wendling (ORCID: https://orcid.org/0000-0002-4687-5780)
- Alain Saraux (ORCID: https://orcid.org/0000-0002-8454-7067)
- Marie‐Elise Truchetet (ORCID: https://orcid.org/0000-0001-8045-0180)
- Pascal Hilliquin
- Guillermo Carvajal Alegria (ORCID: https://orcid.org/0000-0001-5281-5445)
- Valérie Devauchelle‐Pensec (ORCID: https://orcid.org/0000-0003-0432-825X)
- Christophe Richez (ORCID: https://orcid.org/0000-0002-3029-8739)
- Éric Toussirot (ORCID: https://orcid.org/0000-0002-6228-1464)
- Dewi Guellec (ORCID: https://orcid.org/0000-0002-3302-4805)
- Emmanuelle Dernis (ORCID: https://orcid.org/0000-0001-6113-166X)
- Anne Lohse
- Renaud Felten (ORCID: https://orcid.org/0000-0002-4951-4032)
- Guillaume Direz
- Benjamin Dervieux
- Laurent Chiche (ORCID: https://orcid.org/0000-0002-0582-694X)
- Isabelle Chary‐Valckenaere
- Jacques‐Eric Gottenberg (ORCID: https://orcid.org/0000-0002-9469-946X)
- Aleth Perdriger
- Emmanuel Nowak
Institutions
- Université de Bordeaux (FR)
- Inserm (FR)
- Université Rennes 2 (FR)
- Sorbonne Université (FR)
- Centre Hospitalier Universitaire de Besançon (FR)
- Methodology and Quality of Life Unit in Oncology (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Bordeaux Population Health (FR)
- Centre Hospitalier Sud Francilien (FR)
- Centre Hospitalier de Mulhouse (FR)
- Pitié-Salpêtrière Hospital (FR)
- Centre Hospitalier du Mans (FR)
- Centre Hospitalier Régional Universitaire de Brest (FR)
- L'Hôpital Nord Franche-Comté (FR)
- European Hospital (IT)
- Centre Hospitalier des Pays de Morlaix (FR)
- Université de Rennes (FR)
- Université de Strasbourg (FR)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1002/art.43221
- Citations
- 2
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 3.25