Case Report: Endocrine, immune and disease dynamics in a patient with rheumatoid arthritis during flare and medication change
This integrative single-case study clearly demonstrated the importance of process analysis for the evaluation of therapeutic measures in RA. In the studied patient, urinary levels of neopterin, IL-6 and ORM-2 were not found to be appropriate biomarkers of short-term fluctuations in RA disease activity. Instead, the results reported by the patient proved to be a useful tool for ambulatory and longitudinal monitoring of RA.
Authors
- Lennart Seizer (ORCID: https://orcid.org/0000-0003-2868-7919)
- Christoph Garbers (ORCID: https://orcid.org/0000-0003-4939-6950)
- Johanna M. Gostner (ORCID: https://orcid.org/0000-0003-1532-5177)
- Sebastian Säger (ORCID: https://orcid.org/0000-0002-0283-9075)
- Andreas Brandl (ORCID: https://orcid.org/0000-0003-1990-2584)
- Christian Schubert (ORCID: https://orcid.org/0000-0001-7100-0663)
- Melina Licht
Institutions
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- Medizinische Hochschule Hannover (DE)
- Technical University of Munich (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1491475
- Citations
- 2
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 3.34
Funders
- Gemeinsame Bundesausschuss